Structure of PDB 4zfl Chain G

Receptor sequence
>4zflG (length=229) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
ARHVAWLGAPRSLADLVLDPPQGLLVQSYAPRRQKHGLMNADGWGAGFFD
DDGVARRWRSDKPLWGDASFASVAPALRSRCVVAAVRSATIGMPIEPSAS
APFSDGQWLLSHNGLVDRGVLPLTGAAESTVDSAILAALIFSRGLDALGA
TIAEVGELDPNARLNILAANGSRLLATTWGDTLSVLRRPDGVVLASEPYD
DDPGWSDIPDRHLVDVRDAHVVVTPLLEH
3D structure
PDB4zfl Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC.
ChainG
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.118: gamma-glutamyl hercynylcysteine S-oxide hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4NK G H37 G38 L39 M40 R88 S89 A90 T91 M94 G115 D133 S134 R164 H36 G37 L38 M39 R87 S88 A89 T90 M93 G114 D132 S133 R163
BS02 4NK G Y30 W66 Y29 W65
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
Biological Process
GO:0006541 glutamine metabolic process
GO:0052699 ergothioneine biosynthetic process
GO:0052704 ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide

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Molecular Function
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Biological Process
External links
PDB RCSB:4zfl, PDBe:4zfl, PDBj:4zfl
PDBsum4zfl
PubMed26079795
UniProtA0R5M9|EGTC_MYCS2 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase (Gene Name=egtC)

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