Structure of PDB 4xgr Chain G

Receptor sequence
>4xgrG (length=128) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
MMVIDTSALVAMLSDEPDAERFEAAVEADHIRLMSTASYLETALVIEARF
GEPGGRELDLWLHRAAVDLVAVHADQADAARAAYRTYGKAGLNYGDCFSY
GLAKISGQPLLFKGEDFQHTDIATVALP
3D structure
PDB4xgr Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides
ChainG
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide G M11 S13 D14 E22 E26 V44 A47 R48 F49 E56 W60 R63 M12 S14 D15 E23 E27 V45 A48 R49 F50 E57 W61 R64
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004518 nuclease activity
GO:0004540 RNA nuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0045926 negative regulation of growth

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Molecular Function

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Biological Process
External links
PDB RCSB:4xgr, PDBe:4xgr, PDBj:4xgr
PDBsum4xgr
PubMed26150422
UniProtP9WF77|VPC30_MYCTU Ribonuclease VapC30 (Gene Name=vapC30)

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