Structure of PDB 4umm Chain G

Receptor sequence
>4ummG (length=236) Species: 7102 (Heliothis virescens) [Search protein sequence]
VPPLTANQKSLIARLVWYQEGYEQPSEEDLKRVTQTWDSDMPFRQITEMT
ILTVQLIVEFAKGLPGFAKISQSDQITLLKACSSEVMMLRVARRYDAATD
SVLFANNQAYTRDNYRKAGMAYVIEDLLHFCRCMYSMMMDNVHYALLTAI
VIFSDRPGLEQPLLVEEIQRYYLNTLRVYILNQNSASPRCAVIFGKILGI
LTEIRTLGMQNSNMCISLKLKNRKLPPFLEEIWDVA
3D structure
PDB4umm The Palindromic DNA-Bound Usp-Ecr Nuclear Receptor Adopts an Asymmetric Organization with Allosteric Domain Positioning.
ChainG
Resolution11.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 P1A G E309 I339 M342 T343 T346 R383 F397 A398 Y408 N504 E23 I46 M49 T50 T53 R90 F104 A105 Y115 N211
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
GO:0035100 ecdysone binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0035076 ecdysone receptor signaling pathway
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4umm, PDBe:4umm, PDBj:4umm
PDBsum4umm
PubMed24942373
UniProtO18473|ECR_HELVI Ecdysone receptor (Gene Name=EcR)

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