Structure of PDB 4uj4 Chain G

Receptor sequence
>4uj4G (length=175) Species: 9606 (Homo sapiens) [Search protein sequence]
DDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQ
VDGKTIKAQIWDTAGLERYRAITSAYYRGAVGALLVYDIAKHLTYENVER
WLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETS
ALDSTNVEAAFQTILTEIYRIVSQK
3D structure
PDB4uj4 Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11.
ChainG
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GNP G S20 G21 G23 K24 S25 N26 F36 N37 L38 S40 T43 G69 N124 K125 D127 L128 S154 A155 L156 S16 G17 G19 K20 S21 N22 F32 N33 L34 S36 T39 G65 N120 K121 D123 L124 S150 A151 L152
BS02 MG G S25 T43 D66 S21 T39 D62
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:4uj4, PDBe:4uj4, PDBj:4uj4
PDBsum4uj4
PubMed26258637
UniProtP62491|RB11A_HUMAN Ras-related protein Rab-11A (Gene Name=RAB11A)

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