Structure of PDB 4pki Chain G

Receptor sequence
>4pkiG (length=306) Species: 9606 (Homo sapiens) [Search protein sequence]
MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTV
QLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQG
FESATFLGYFKSGLKYKKGGVASGFGYKPVPDEEPNSTDVEETLERIKNN
DPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVAYA
LAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQP
LGNKVEMEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRR
LADLTG
3D structure
PDB4pki Actin cytoskeleton. Mechanism of actin filament pointed-end capping by tropomodulin.
ChainG
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA G D136 G141 A143 D85 G90 A92
BS02 CA G G92 D93 E124 V172 G41 D42 E73 V121
Gene Ontology
Molecular Function
GO:0005523 tropomyosin binding
GO:0051015 actin filament binding
Biological Process
GO:0051694 pointed-end actin filament capping

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Molecular Function

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Biological Process
External links
PDB RCSB:4pki, PDBe:4pki, PDBj:4pki
PDBsum4pki
PubMed25061212
UniProtP06396|GELS_HUMAN Gelsolin (Gene Name=GSN);
P28289

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