Structure of PDB 4j5i Chain G

Receptor sequence
>4j5iG (length=264) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
QVTVTKLGAHIGARIDGVRVGGDLSPATVSAINAALLEHKVIFFSGQDHL
DDAGQLEFAELLGTPTVAHPTLAEGAEQLLPIDANSWHTDVTFVDRIPKA
SLLRAVTLPSYGGTTAWASTEAAYQQLPAPLRTLADNLWAVHTNRDYYEV
EHPVVRVHPETGERVLLLGHFVKSFVGLKDTESAALFRLFQDRITRLENT
VRWSWKPGDLAIWDNRATQHYAVADYDDQYRRLNRVTLAGDIPVDVYGER
SRVIAGDASSYSPV
3D structure
PDB4j5i Increasing the structural coverage of tuberculosis drug targets.
ChainG
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H95 D97 H248 R263
Catalytic site (residue number reindexed from 1) H88 D90 H220 R235
Enzyme Commision number 1.14.11.17: taurine dioxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE G H95 D97 H248 H88 D90 H220
Gene Ontology
Molecular Function
GO:0000908 taurine dioxygenase activity
GO:0016491 oxidoreductase activity
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:4j5i, PDBe:4j5i, PDBj:4j5i
PDBsum4j5i
PubMed25613812
UniProtA0QZ23

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