Structure of PDB 4gwq Chain G

Receptor sequence
>4gwqG (length=170) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
MNVTPLDELQWKSPEWIQVFGLRTENVLDYFAESPFFDKTSNNQVIKMQR
QFSQLNDPNAFAYVDPARRQILFKYPMYMQLEEELMKLDGTEYVLSSVRE
PDFWVIRKQRRTNNSGVGSAKGPEIIPLQDYYIIGANIYQSPTIFKIVQS
RLMSTSYHLNSTLESLYDLI
3D structure
PDB4gwq Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II.
ChainG
Resolution4.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide G L9 Q10 L9 Q10
Gene Ontology
Molecular Function
GO:0003712 transcription coregulator activity
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0032968 positive regulation of transcription elongation by RNA polymerase II
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051123 RNA polymerase II preinitiation complex assembly
GO:0060261 positive regulation of transcription initiation by RNA polymerase II
Cellular Component
GO:0005634 nucleus
GO:0016592 mediator complex
GO:0070847 core mediator complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4gwq, PDBe:4gwq, PDBj:4gwq
PDBsum4gwq
PubMed23071300
UniProtP38782|MED6_YEAST Mediator of RNA polymerase II transcription subunit 6 (Gene Name=MED6)

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