Structure of PDB 4d6o Chain G

Receptor sequence

>4d6oG (length=176) [Search protein sequence]

VSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAPLM
QFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMREQ
IAFIKGLYVAEGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLDDH
RHGVYVLNISLRDRIKFVHTILSSHL

3D structure

PDB

4d6o Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.

Chain

Resolution

2.2 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	G	K86 Y89 N93 R97	K80 Y83 N87 R91
BS02	dna	G	G20 D21 G22 Y25 Y29 R33 R37 T41 Q42 K43 T76 R77 R124 T150 H152 D154 R157 N164 S166 L167	G14 D15 G16 Y19 Y23 R27 R31 T35 Q36 K37 T70 R71 R118 T144 H146 D148 R151 N158 S160 L161
BS03	dna	G	N32 R33 S34 E35 Y36 R37 S67 K68 Q70 D75 R81 S83 K85 E117 D119 K120 R124 R126 W128 N129 K130 D155 H158 V160	N26 R27 S28 E29 Y30 R31 S61 K62 Q64 D69 R75 S77 K79 E111 D113 K114 R118 R120 W122 N123 K124 D149 H152 V154
BS04	MG	G	D21 A116	D15 A110
BS05	MG	G	G20 E117	G14 E111

Gene Ontology

	Molecular Function
GO:0004519	endonuclease activity

	Biological Process
GO:0006314	intron homing
GO:0016539	intein-mediated protein splicing

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Molecular Function

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Biological Process

External links

PDB	RCSB:4d6o, PDBe:4d6o, PDBj:4d6o
PDBsum	4d6o
PubMed	25486305
UniProt	P21505\|DMO1_DESMO Homing endonuclease I-DmoI

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