Structure of PDB 3zkd Chain G

Receptor sequence
>3zkdG (length=378) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
DEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMA
GYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKF
DSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLK
QGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLT
DERVPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVE
IAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLL
PNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQL
THWFEANPTDAKVVVNKAVSSAQARIAA
3D structure
PDB3zkd Mycobacterium Tuberculosis DNA Gyrase ATPase Domain Structures Suggest a Dissociative Mechanism that Explains How ATP Hydrolysis is Coupled to Domain Motion.
ChainG
Resolution2.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP G N52 E56 G83 I84 V99 G106 G107 K108 Y114 G119 L120 H121 G122 V123 G124 V125 K372 N43 E47 G74 I75 V90 G97 G98 K99 Y105 G110 L111 H112 G113 V114 G115 V116 K330
BS02 MG G E48 N52 E39 N43
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:3zkd, PDBe:3zkd, PDBj:3zkd
PDBsum3zkd
PubMed24015710
UniProtP9WG45|GYRB_MYCTU DNA gyrase subunit B (Gene Name=gyrB)

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