Structure of PDB 3s2i Chain G

Receptor sequence
>3s2iG (length=340) Species: 264198 (Cupriavidus pinatubonensis JMP134) [Search protein sequence]
AMMKAAVVRAFGAPLTIDEVPVPQPGPGQVQVKIEASGVCHTDLHAADGD
WPVKPTLPFIPGHEGVGYVSAVGSGVSRVKEGDRVGVPWLYSACGYCEHC
LQGWETLCEKQQNTGYSVNGGYGEYVVADPNYVGLLPDKVGFVEIAPILC
AGVTVYKGLKVTDTRPGQWVVISGIGGLGHVAVQYARAMGLRVAAVDIDD
AKLNLARRLGAEVAVNARDTDPAAWLQKEIGGAHGVLVTAVSPKAFSQAI
GMVRRGGTIALNGLPPGDFGTPIFDVVLKGITIRGSIVGTRSDLQESLDF
AAHGDVKATVSTAKLDDVNDVFGRLREGKVEGRVVLDFSR
3D structure
PDB3s2i Crystal structures and furfural reduction mechanism of a bacterial zinc-dependent alcohol dehydrogenase
ChainG
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C42 H43 T44 H47 H65 E66 C96 C99 C102 C110 Q114 C152 T156 R335
Catalytic site (residue number reindexed from 1) C40 H41 T42 H45 H63 E64 C94 C97 C100 C108 Q112 C150 T154 R333
Enzyme Commision number 1.1.1.1: alcohol dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD G H43 T44 H47 T156 G179 L180 D199 I200 T241 A242 V243 S244 A247 N264 G265 L266 S288 I289 V290 H41 T42 H45 T154 G177 L178 D197 I198 T239 A240 V241 S242 A245 N262 G263 L264 S286 I287 V288
BS02 ZN G C42 H65 C152 C40 H63 C150
BS03 ZN G C96 C99 C102 C110 C94 C97 C100 C108
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:3s2i, PDBe:3s2i, PDBj:3s2i
PDBsum3s2i
PubMed
UniProtQ46UZ9

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