Structure of PDB 3jcm Chain G

Receptor sequence
>3jcmG (length=734) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
PSFLDQEPPAGYVPGIGRGATGFKTLELKLAQKKKKRANEKSNVKRQFAD
LKESLAAVTESEWMDIPDATDFTRRNKRNRIQEQLNRKTYAAPDSLIPGN
VDLNKLTEEREKLLQSQIDENLRVNSLSDATLEDLQKMRTILKSYRKADP
TNPQGWIASARLEEKARKFSVAKKIIENGCQPRSSDIWLENIRLHESDVH
YCKTLVATAINFNPLLWFKAIDLESTTVNKYRVVRKALQEIPRDEGLWKL
AVSFEADKAQVIKMLEKATQFIPQSMDLLTAYTNLQSYHNAKMTSFRKIL
PQEPEIWIISTLLEERNNPDIPVDKLVSEGLLELSKNGYKATLSAKRAEA
LNDAPNSTCQAIVYAILEWLREYESELNNVDQILEKMPHSKKKLIQWDPC
DTVLWSRKMATESYHKIEELLAFFQEQTKNSDDIRANMRKSPGLLMMYVS
EYWKDTRQTLVLIDQIIDNLDLRFFKIKLLGRSRDFFQQTFSSLEDFKSG
TERLYYKYVNFNEEAIKFLNERCLKSICHKFFLQLGQIYHSMGEMSRETY
LSGTRLVPNCPLLWVSLSKIDEIDVRARSILDRGLLKNPDDVLFYIAKIQ
MEIRLGNLDQAELLVTQALQKFPSNALLWVEQIKLFKHGNKSSLKKTIFQ
DALRRTQNDHRVLLEIGVSFYAEAQYETSLKWLERALKKCYGDTWVWLFR
TYARLGKDTVDLYNMFDQCECTPREILLRLMNDK
3D structure
PDB3jcm The 3.8 angstrom structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis
ChainG
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna G N132 K133 R136 Q140 K144 S788 K791 T792 N76 K77 R80 Q84 K88 S643 K646 T647
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000244 spliceosomal tri-snRNP complex assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0008150 biological_process
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005682 U5 snRNP
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP
GO:0071013 catalytic step 2 spliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3jcm, PDBe:3jcm, PDBj:3jcm
PDBsum3jcm
PubMed26743623
UniProtP19735|PRP6_YEAST Pre-mRNA-splicing factor 6 (Gene Name=PRP6)

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