Structure of PDB 3jah Chain G

Receptor sequence

>3jahG (length=241) Species: 9986 (Oryctolagus cuniculus)

KVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLK
VPPAINQFTQVLDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGK
GDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCR
KMGVPYCILKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTN
YNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG

3D structure

• PDB: 3jah Structural basis for stop codon recognition in eukaryotes.
• Chain: G
• Resolution: 3.45 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	G	E33 K34 R35 K37 F39 G40 I41 Q43 I45 Q46 P47 L51 R53 F54 V55 K56 P58 Y60 R62 K72 R73 L74 E105 K107 Q108 K110 Q112 R113 R132 G139 V140 N141 T142 V161 D162 P163 L166 K187 R192 R196 K197 T198 C199 T200 L242 P244 K245 S246 R249	E8 K9 R10 K12 F14 G15 I16 Q18 I20 Q21 P22 L26 R28 F29 V30 K31 P33 Y35 R37 K47 R48 L49 E80 K82 Q83 K85 Q87 R88 R107 G114 V115 N116 T117 V136 D137 P138 L141 K162 R167 R171 K172 T173 C174 T175 L217 P219 K220 S221 R224
BS02	rna	G	T52 Y60 I61 Q64 R65 R89 H159 D160 K185 R189	T27 Y35 I36 Q39 R40 R64 H134 D135 K160 R164

Gene Ontology

Biological Process

• GO:0042254 ribosome biogenesis

Cellular Component

• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:3jah, PDBe:3jah, PDBj:3jah
• PDBsum: 3jah
• PubMed: 26245381
• UniProt: G1STW0|RL7A_RABIT Large ribosomal subunit protein eL8 (Gene Name=RPL7A)