Structure of PDB 3g76 Chain G

Receptor sequence
>3g76G (length=95) Species: 9606 (Homo sapiens) [Search protein sequence]
STNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFH
CGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHS
3D structure
PDB3g76 Structural basis for bivalent smac-mimetics recognition in the IAP protein family
ChainG
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN G C300 C303 H320 C327 C48 C51 H68 C75
BS02 CZ3 G V298 K299 G306 L307 T308 D309 E314 Q319 W323 Y324 V46 K47 G54 L55 T56 D57 E62 Q67 W71 Y72
External links
PDB RCSB:3g76, PDBe:3g76, PDBj:3g76
PDBsum3g76
PubMed19393243
UniProtP98170|XIAP_HUMAN E3 ubiquitin-protein ligase XIAP (Gene Name=XIAP)

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