Structure of PDB 3ec7 Chain G

Receptor sequence
>3ec7G (length=335) Species: 99287 (Salmonella enterica subsp. enterica serovar Typhimurium str. LT2) [Search protein sequence]
TLKAGIVGIGMIGSDHLRRLANTVSGVEVVAVCDIVAGRAQAALDKYAIE
AKDYNDYHDLINDKDVEVVIITASNEAHADVAVAALNANKYVFCEKPLAV
TAADCQRVIEAEQKNGKRMVQIGFMRRYDKGYVQLKNIIDSGEIGQPLMV
HGRHYNASTVPEYKTPQAIYETLIHEIDVMHWLLNEDYKTVKVYFPRQSS
LVTTLRDPQLVVMETTSGINIVVEVFVNCQYGYDIHCDVTGEKGMAELPT
VASAAVRKAAKYSTDILVDWKQRFIDAYDIEFQDFFDRLNAGLPPAGPTS
WDGYLAAVTADACVKSQETGNTEIVELPSKPDFYK
3D structure
PDB3ec7 Crystal Structure of Putative Dehydrogenase from Salmonella typhimurium LT2
ChainG
Resolution2.15 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K97 H176
Catalytic site (residue number reindexed from 1) K96 H175
Enzyme Commision number 1.1.1.18: inositol 2-dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD G G11 M12 I13 D35 I36 R40 A74 S75 N76 H79 E96 K97 M126 Y279 G10 M11 I12 D34 I35 R39 A73 S74 N75 H78 E95 K96 M125 Y278
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0050112 inositol 2-dehydrogenase (NAD+) activity
Biological Process
GO:0019310 inositol catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3ec7, PDBe:3ec7, PDBj:3ec7
PDBsum3ec7
PubMed
UniProtQ8ZK57|IOLG_SALTY Inositol 2-dehydrogenase (Gene Name=iolG)

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