Structure of PDB 3bze Chain G

Receptor sequence
>3bzeG (length=273) Species: 9606 (Homo sapiens) [Search protein sequence]
SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPW
MEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGC
ELGPDRRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDAS
EAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPS
GEEQRYTCHVQHEGLPEPVTLRW
3D structure
PDB3bze Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors
ChainG
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide G R65 D69 Q72 R64 D68 Q71
BS02 peptide G Y7 E63 S66 A67 I73 N77 Y84 W97 W133 S143 K146 E152 H155 Q156 Y159 W167 Y171 Y6 E62 S65 A66 I72 N76 Y83 W96 W132 S142 K145 E151 H154 Q155 Y158 W166 Y170
External links
PDB RCSB:3bze, PDBe:3bze, PDBj:3bze
PDBsum3bze
PubMed18339401
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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