Structure of PDB 3bsu Chain G

Receptor sequence
>3bsuG (length=50) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHMFYAVRRGRKTGVFLTWNECRAQVDRFPAARFKKFATEDEAWAFVRK
3D structure
PDB3bsu Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD.
ChainG
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna G G24 D51 R52 F53 P54 A55 G1 D28 R29 F30 P31 A32 PDBbind-CN: Kd=0.2uM
BS02 dna G Y29 W43 F58 K60 Y6 W20 F35 K37 PDBbind-CN: Kd=0.2uM
External links
PDB RCSB:3bsu, PDBe:3bsu, PDBj:3bsu
PDBsum3bsu
PubMed18337749
UniProtO60930|RNH1_HUMAN Ribonuclease H1 (Gene Name=RNASEH1)

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