Structure of PDB 3ai3 Chain G

Receptor sequence

>3ai3G (length=263) Species: 38308 (Gluconobacter frateurii) [Search protein sequence]

MDMGISGKVAVITGSSSGIGLAIAEGFAKEGAHIVLVARQVDRLHEAARS
LKEKFGVRVLEVAVDVATPEGVDAVVESVRSSFGGADILVNNAGTGSNET
IMEAADEKWQFYWELLVMAAVRLARGLVPGMRARGGGAIIHNASICAVQP
LWYEPIYNVTKAALMMFSKTLATEVIKDNIRVNCINPGLILTPDWIKTAK
ELTKDNGGDWKGYLQSVADEHAPIKRFASPEELANFFVFLCSERATYSVG
SAYFVDGGMLKTL

3D structure

PDB

3ai3 The Crystal Structure of l-Sorbose Reductase from Gluconobacter frateurii Complexed with NADPH and l-Sorbose

Chain

Resolution

1.8 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	S144 Y157
Catalytic site (residue number reindexed from 1)	S144 Y157
Enzyme Commision number	1.1.1.289: sorbose reductase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	NDP	G	G14 S16 S17 G18 I19 A38 R39 Q40 R43 D65 V66 N92 G94 N142 S144 Y157 K161 P187 I190 T192	G14 S16 S17 G18 I19 A38 R39 Q40 R43 D65 V66 N92 G94 N142 S144 Y157 K161 P187 I190 T192
BS02	SOL	G	G96 S144 E154 Y157 W195	G96 S144 E154 Y157 W195
BS03	SOE	G	H45 A48 R49 K52 V59 E61	H45 A48 R49 K52 V59 E61
BS04	SOE	G	I5 K8 R181 C241 E243	I5 K8 R181 C241 E243
BS05	SOE	G	A252 F254 L263	A252 F254 L263

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0016491	oxidoreductase activity

View graph for
Molecular Function

External links

PDB	RCSB:3ai3, PDBe:3ai3, PDBj:3ai3
PDBsum	3ai3
PubMed	21277857
UniProt	A4PB64

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