Structure of PDB 2vs7 Chain G

Receptor sequence

>2vs7G (length=177) [Search protein sequence]

ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAP
LMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMR
EQIAFIKGLYVAEGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLD
DHRHGVYVLNISLRDRIKFVHTILSSH

3D structure

PDB

2vs7 Crystal Structure of I-Dmoi in Complex with its Target DNA Provides New Insights Into Meganuclease Engineering.

Chain

Resolution

2.05 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

3.1.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	G	K86 Y89 N93 R97	K82 Y85 N89 R93
BS02	dna	G	G20 D21 G22 Y25 Y29 R33 R37 T41 Q42 K43 T76 R77 E117 R124 T150 H152 D154 R157 N164 S166 L167	G16 D17 G18 Y21 Y25 R29 R33 T37 Q38 K39 T72 R73 E113 R120 T146 H148 D150 R153 N160 S162 L163
BS03	dna	G	N32 R33 S34 E35 Y36 R37 S67 K68 Q70 D75 R81 S83 S84 K85 E117 G118 D119 K120 R126 W128 N129 K130 D155 H158 V160	N28 R29 S30 E31 Y32 R33 S63 K64 Q66 D71 R77 S79 S80 K81 E113 G114 D115 K116 R122 W124 N125 K126 D151 H154 V156
BS04	CA	G	D21 A116	D17 A112

Gene Ontology

	Molecular Function
GO:0004519	endonuclease activity

	Biological Process
GO:0006314	intron homing
GO:0016539	intein-mediated protein splicing

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:2vs7, PDBe:2vs7, PDBj:2vs7
PDBsum	2vs7
PubMed	18974222
UniProt	P21505\|DMO1_DESMO Homing endonuclease I-DmoI

[Back to BioLiP]