Structure of PDB 2hd0 Chain G

Receptor sequence
>2hd0G (length=127) [Search protein sequence]
SHMQASLLKVPYFVRVQGLLRICALARKIAGGHYVQMAIIKLGALTGTYV
YNHLTPLRDWAHNGLRDLAVAVEPVVFSRMETKLITWGADTAACGDIING
LPVSARRGQEILLGPADGMVSKGWRLL
3D structure
PDB2hd0 Structure of the catalytic domain of the hepatitis C virus NS2-3 protease.
ChainG
Resolution2.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.21.98: hepacivirin.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DMU G L98 V104 L8 V14
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity

View graph for
Molecular Function
External links
PDB RCSB:2hd0, PDBe:2hd0, PDBj:2hd0
PDBsum2hd0
PubMed16862121
UniProtP27958|POLG_HCV77 Genome polyprotein

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