Structure of PDB 1t44 Chain G

Receptor sequence
>1t44G (length=144) Species: 9606 (Homo sapiens) [Search protein sequence]
EHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLR
NGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFES
ATFLGYFKSGLKYKKGGVASGFKHVETQEKNPLPSKETIEQEKQ
3D structure
PDB1t44 Structural basis of actin sequestration by thymosin-beta4: implications for WH2 proteins.
ChainG
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA G D109 G114 A116 D82 G87 A89
BS02 CA G G65 D66 E97 V145 G38 D39 E70 V118
Gene Ontology
Molecular Function
GO:0003785 actin monomer binding
GO:0051015 actin filament binding
Biological Process
GO:0007015 actin filament organization

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Molecular Function

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Biological Process
External links
PDB RCSB:1t44, PDBe:1t44, PDBj:1t44
PDBsum1t44
PubMed15329672
UniProtP06396|GELS_HUMAN Gelsolin (Gene Name=GSN)

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