Structure of PDB 1pzj Chain G

Receptor sequence
>1pzjG (length=103) Species: 666 (Vibrio cholerae) [Search protein sequence]
TPQNITDLCAEYHNTQIHTLNDKIFSYTESLAGKREMAIITFKNGATFQV
EVPGSQHIDSQKKAIERMKDTLRIAYLTEAKVEKLCVWNNKTPHAIAAIS
MAN
3D structure
PDB1pzj 3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies
ChainG
Resolution1.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 J15 G G33 R35 G33 R35
BS02 15B G Y12 E51 Q56 H57 Q61 W88 N90 K91 Y12 E51 Q56 H57 Q61 W88 N90 K91 MOAD: ic50=0.32mM
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:1pzj, PDBe:1pzj, PDBj:1pzj
PDBsum1pzj
PubMed14980603
UniProtQ57193

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