Structure of PDB 1pk8 Chain G

Receptor sequence
>1pk8G (length=293) Species: 10116 (Rattus norvegicus) [Search protein sequence]
AARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGF
SVDMEVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSV
YNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVK
MGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQKI
GQNYKAYMRTSVNWKTNAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEA
LHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQA
3D structure
PDB1pk8 Tetramerization and ATP binding by a protein comprising the A, B, and C domains of rat synapsin I.
ChainG
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA G E373 E386 E249 E262
BS02 ATP G V267 K269 H274 S275 G276 K279 E305 F307 I308 W335 T337 N338 L375 V148 K150 H155 S156 G157 K160 E186 F188 I189 W214 T216 N217 L251 MOAD: Kd=120nM
Gene Ontology
Biological Process
GO:0007269 neurotransmitter secretion
Cellular Component
GO:0008021 synaptic vesicle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1pk8, PDBe:1pk8, PDBj:1pk8
PDBsum1pk8
PubMed14688264
UniProtP09951|SYN1_RAT Synapsin-1 (Gene Name=Syn1)

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