Structure of PDB 1mzn Chain G

Receptor sequence
>1mznG (length=212) Species: 9606 (Homo sapiens) [Search protein sequence]
DMPVERILEAELAVEPDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDD
QVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIF
DRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKV
YASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP
IDTFLMEMLEAP
3D structure
PDB1mzn Molecular Recognition of Agonist Ligands by RXRs
ChainG
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide G V3280 K3284 L3294 Q3297 V3298 R3302 F3450 E3453 V34 K38 L48 Q51 V52 R56 F204 E207
BS02 BM6 G I3268 A3272 N3306 L3309 I3310 F3313 R3316 L3326 A3327 C3432 F3439 I22 A26 N60 L63 I64 F67 R70 L80 A81 C186 F193
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Cellular Component
External links
PDB RCSB:1mzn, PDBe:1mzn, PDBj:1mzn
PDBsum1mzn
PubMed11981034
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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