Structure of PDB 7q9b Chain FFF

Receptor sequence

>7q9bFFF (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE

3D structure

PDB

7q9b Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.

Chain

FFF

Resolution

3.24 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	FFF	M5 Y7 E63 K66 H70 T73 V76 D77 L81 Y99 Y116 T143 K146 W147 Q155 Y159 W167 Y171	M5 Y7 E63 K66 H70 T73 V76 D77 L81 Y99 Y116 T143 K146 W147 Q155 Y159 W167 Y171

External links

PDB	RCSB:7q9b, PDBe:7q9b, PDBj:7q9b
PDBsum	7q9b
PubMed	37490916
UniProt	A0A140T913

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