Structure of PDB 8ipa Chain FA

Receptor sequence
>8ipaFA (length=185) Species: 4565 (Triticum aestivum) [Search protein sequence]
KTILASETMEIPEEVTVKVSAKMISVTGPRGTLTRNFKHLNLDFQLQEGG
RKLKVDAWFGTRKTMAAIRTAISHVQNLITGVTKGFRYKMRFVYAHFPIN
ASITAANRGIEIRNFLGEKKVRKVDMLDGVTILRSEKVKDEIVLDGNDIE
LVSRSAALINQKCHVKNKDIRKFLDGIYVSDKGAI
3D structure
PDB8ipa Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
ChainFA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna FA K2 A22 H40 N42 L43 W59 R63 K64 A67 T71 S74 H75 N78 H97 F98 E119 K120 K121 S154 R155 L159 Q162 K169 D170 R172 K173 F174 K1 A21 H39 N41 L42 W58 R62 K63 A66 T70 S73 H74 N77 H96 F97 E118 K119 K120 S153 R154 L158 Q161 K168 D169 R171 K172 F173
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8ipa, PDBe:8ipa, PDBj:8ipa
PDBsum8ipa
PubMed38267667
UniProtW5I5G5

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