Structure of PDB 6sgb Chain F7

Receptor sequence

>6sgbF7 (length=662) Species: 5702 (Trypanosoma brucei brucei)

RLAAAAVKAAEWYAAENRRKQKGGDVIREKVDCTAPLWFDDTEQNLLARE
QHVRSPAYRELHRPALTNAAMGLYGGEPGFEKAHRVWVDPDRPHIKHIYN
QTALARNLRYARYGYFKRDMHLLDVDKLVRHARLLPTPGRLLTDFLYQRV
PLPDKSCAALIRYQRQQIEMLEVWGRHASFQCAVEMFERMIVTNIPPVEV
GVETHGEMVLCAAACGKWEEGWNVYANRARELEKESPESFILNTFFFDAL
LTLCVAAGRVSEGIDTLEEVIKRNLRPRGTMLNKAMILYSILGEQMSKHE
ASRYLCEPEEVEKMGLEVWSLFDFYQLPRTTASIEAYMRMCCAFNKPTLV
LKAQGFADASDIRLSIECFHWLVYAIRGVAGFGDYVMDVLSQLRPRGLTP
DFVLFTLSFMYCALQRDGELALAIFDQHFVHQNMNPTPEMVLLFIQACSN
CEEPTAVMLERSETLIKRLEAVGSSVDLISPIYDQFLELCAHLGAVASGF
SALKRIVGFGKPLTTRMINSLLLANSNAISSNGSLSMTEELVGFFTLLKI
RPNADTEICVNLCRDAFGESPVVNDFIKVIGESLQGDSEKGEAPQYDEDI
PVIQVPPHELRQLRTEWKLSPRDIVLRRFGQHTKPPGKAALDVGSMRGSV
IPFGRSPGEQLV

3D structure

• PDB: 6sgb Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
• Chain: F7
• Resolution: 3.3 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	F7	A78 A79	A69 A70
BS02	peptide	F7	H509 S537 D572 D614	H492 S520 D555 D597
BS03	rna	F7	T76 N77 Y83 A92 Q110 T111 R115 L117 R118 R121 G123 Y124 K126 R142 L143 T146 R149 D153 Y156 Q157 R158 Q176 A187 S188 C191 R644 Q648 H649 T650 R664 S666 R672 S673	T67 N68 Y74 A83 Q101 T102 R106 L108 R109 R112 G114 Y115 K117 R133 L134 T137 R140 D144 Y147 Q148 R149 Q167 A178 S179 C182 R627 Q631 H632 T633 R647 S649 R655 S656

Gene Ontology

Molecular Function

• GO:0003729 mRNA binding

Cellular Component

• GO:0005739 mitochondrion
• GO:0005763 mitochondrial small ribosomal subunit

External links

• PDB: RCSB:6sgb, PDBe:6sgb, PDBj:6sgb
• PDBsum: 6sgb
• PubMed: 31515389
• UniProt: Q57UW6