Structure of PDB 8zly Chain F

Receptor sequence
>8zlyF (length=501) Species: 171101 (Streptococcus pneumoniae R6) [Search protein sequence]
MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAKLIEAGA
NTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFE
GEAKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVL
VDDGKLGLRVVAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAE
RDNDDIRFGLEQGINFIAISFVRTAKDVNEVRAICEETGNGHVQLFAKIE
NQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIIKKVNAAGK
VVITATNMLETMTEKPRATRSEVSDVFNAVIDGTDATMLSGESANGKYPL
ESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVKDATSSMDI
KLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTV
R
3D structure
PDB8zly Structural basis of nucleotide selectivity in pyruvate kinase.
ChainF
Resolution1.89 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FBP F S382 T384 T407 K408 T409 H411 T412 V490 R491 S382 T384 T407 K408 T409 H411 T412 V490 R491
BS02 MG F E250 D274 E250 D274
BS03 UDP F P13 R54 N56 H59 R95 K184 G341 N345 P13 R54 N56 H59 R95 K184 G341 N345
BS04 OXL F K248 E250 A271 G273 D274 T306 K248 E250 A271 G273 D274 T306
Gene Ontology
Molecular Function
GO:0004743 pyruvate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0046872 metal ion binding
Biological Process
GO:0006096 glycolytic process
GO:0016310 phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8zly, PDBe:8zly, PDBj:8zly
PDBsum8zly
PubMed39009072
UniProtQ8DQ84

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