Structure of PDB 8wkl Chain F

Receptor sequence
>8wklF (length=304) Species: 4060 (Rauvolfia serpentina) [Search protein sequence]
LKEILIEAPSYAPNSFTFDSTNKGFYTSVQDGRVIKYEGPNSGFVDFAYA
SPYWNKAFCENSTDAEKRPLCGRTYDISYNLQNNQLYIVDCYYHLSVVGS
EGGHATQLATSVDGVPFKWLYAVTVDQRTGIVYFTDVSTLYDDRGVQQIM
DTSDKTGRLIKYDPSTKETTLLLKELHVPGGAEVSADSSFVLVAEFLSHQ
IVKYWLEGPKKGTAEVLVKIPNPGNIKRNADGHFWVSSSEELDGNMHGRV
DPKGIKFDEFGNILEVIPLPPPFAGEHFEQIQEHDGLLYIGTLFHGSVGI
LVYD
3D structure
PDB8wkl Proxy-approach in understanding the bisubstrate activity of strictosidine synthases.
ChainF
Resolution2.67 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.3.3.2: Transferred entry: 3.5.99.13.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 F66 F Y151 E309 Y121 E279
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016844 strictosidine synthase activity
Biological Process
GO:0009058 biosynthetic process
GO:0009820 alkaloid metabolic process
Cellular Component
GO:0005773 vacuole
GO:0012505 endomembrane system

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8wkl, PDBe:8wkl, PDBj:8wkl
PDBsum8wkl
PubMed38354931
UniProtP68175|STSY_RAUSE Strictosidine synthase (Gene Name=STR1)

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