Structure of PDB 8w7c Chain F

Receptor sequence
>8w7cF (length=174) Species: 9606 (Homo sapiens) [Search protein sequence]
LIPIVVDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHM
YINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMR
HSLPNSRIMIHQPSATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESA
MERDRYMSPMEAQEFGILDKVLVH
3D structure
PDB8w7c Activation of mitochondrial Caseinolytic Protease P (ClpP) induces selective cancer cell lethality
ChainF
Resolution3.0 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 R89 F I100 L104 F105 S108 T135 Y138 I33 L37 F38 S41 T68 Y71
BS02 R89 F R78 E82 I84 H116 Y118 W146 R11 E15 I17 H49 Y51 W79
External links
PDB RCSB:8w7c, PDBe:8w7c, PDBj:8w7c
PDBsum8w7c
PubMed
UniProtQ16740|CLPP_HUMAN ATP-dependent Clp protease proteolytic subunit, mitochondrial (Gene Name=CLPP)

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