Structure of PDB 8v1l Chain F

Receptor sequence
>8v1lF (length=128) Species: 9606 (Homo sapiens) [Search protein sequence]
VMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGADAVYGQ
KEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNQALRRFMQ
TFVLAPEGSVANKFYVHNDIFRYQDEVF
3D structure
PDB8v1l Identification of small molecule inhibitors of G3BP-driven stress granule formation.
ChainF
Resolution2.68 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Y9M F P6 L10 V11 F15 Q18 M29 R32 F33 Q58 N122 K123 F124 P5 L9 V10 F14 Q17 M28 R31 F32 Q50 N112 K113 F114
External links
PDB RCSB:8v1l, PDBe:8v1l, PDBj:8v1l
PDBsum8v1l
PubMed38284934
UniProtQ13283|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (Gene Name=G3BP1)

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