Structure of PDB 8r5h Chain F

Receptor sequence
>8r5hF (length=111) Species: 9606 (Homo sapiens) [Search protein sequence]
KVSEQLKAASGILKEMFAKCHAAYAWPFYKPVDVEALGLHDYADIIKHPM
DMSTIKSKLEAREYRDAQEFGADVRLMFSNAYKYNPPDHEVVAMARKLQD
VFEMRFAKMPD
3D structure
PDB8r5h Cullin-RING ligases target substrates with geometrically optimized catalytic partners
ChainF
Resolution3.44 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 759 F W374 P375 L385 L387 W26 P27 L37 L39
External links
PDB RCSB:8r5h, PDBe:8r5h, PDBj:8r5h
PDBsum8r5h
PubMed38382526
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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