Structure of PDB 8qw7 Chain F

Receptor sequence
>8qw7F (length=148) Species: 9606 (Homo sapiens) [Search protein sequence]
RPVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRI
HSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLK
ERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIA
3D structure
PDB8qw7 Targeting cancer with small molecule pan-KRAS degraders
ChainF
Resolution2.36 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 X53 F W88 Y98 P99 R107 I109 H110 Y112 H115 W117 W29 Y39 P40 R48 I50 H51 Y53 H56 W58
External links
PDB RCSB:8qw7, PDBe:8qw7, PDBj:8qw7
PDBsum8qw7
PubMed
UniProtP40337|VHL_HUMAN von Hippel-Lindau disease tumor suppressor (Gene Name=VHL)

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