Structure of PDB 8q6r Chain F

Receptor sequence
>8q6rF (length=211) Species: 9606 (Homo sapiens) [Search protein sequence]
GVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTH
ICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRK
FDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQ
RLCTPLLPKYPPTVSMVEGQGEKNVTFWGRPLPRCEELQGQKLVVEEKRP
CLHVPACKDPE
3D structure
PDB8q6r Structure of complement FP in complex with the TPP-3077 VHH
ChainF
Resolution1.9 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUC F T272 C273 T18 C19
BS02 MAN F E317 W318 R348 E63 W64 R94
BS03 MAN F S320 W321 R346 S66 W67 R92
BS04 MAN F E323 W324 E69 W70
BS05 MAN F S381 W382 C439 S127 W128 C185
BS06 MAN F T387 W388 R401 T133 W134 R147
BS07 MAN F E384 W385 R403 E130 W131 R149
BS08 MAN F G259 W260 R282 A297 G5 W6 R28 A43
BS09 MAN F P262 W263 R302 P8 W9 R48
External links
PDB RCSB:8q6r, PDBe:8q6r, PDBj:8q6r
PDBsum8q6r
PubMed
UniProtP27918|PROP_HUMAN Properdin (Gene Name=CFP)

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