Structure of PDB 8of4 Chain F

Receptor sequence
>8of4F (length=87) Species: 8355 (Xenopus laevis) [Search protein sequence]
KRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENV
IRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
3D structure
PDB8of4 Binding to nucleosome poises SIRT6 for histone H3 de-acetylation
ChainF
Resolution2.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna F R35 R45 I46 S47 G48 R78 K79 T80 R20 R30 I31 S32 G33 R63 K64 T65
BS02 dna F K16 R17 P32 R36 K1 R2 P17 R21
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:8of4, PDBe:8of4, PDBj:8of4
PDBsum8of4
PubMed38415718
UniProtP62799|H4_XENLA Histone H4

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