Structure of PDB 8k9g Chain F

Receptor sequence
>8k9gF (length=450) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence]
MRNKIFISHATPEDDDFTRWLSLKLIGLGYEVWCDILFLDKGVDFWSTIE
KEIRENTCKFLIVSSTAGNKREGVLKELAVATKVKKHLQDDMFIIPLAID
ENLSYDDINIEIVRLNAIDFKKSWAKGLQDLLDAFEKQNVPKKPPDHSKS
NLLYQQIFLHDKQAIEKEETYDSNWFPIISFPNELRFHRYDWRLPKQFDV
RTLAFPAIRYKEYLCTFAWEYDFIHQLPKTETYNGQESIRISTSDILSGR
YDTDFIRNYECQRLIVQLINKAFELRMKDKNVREYQMSKTFAYWIEKGKL
EKDKFEKIKLVGKQKNKYWHFGISAAGKLYPSPVLMVSSHIIFTMDGINL
IKSKSIQHSSRRKQGKNWWNDKWREKLLAFIRFLSDDQNAIYLNVGSEEK
ILISNKPLKFFGKMSYVTPSEVTLEEESVLADINNFEEDTEDLDELEDIE
3D structure
PDB8k9g Nucleic acid-triggered NADase activation of a short prokaryotic Argonaute.
ChainF
Resolution3.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna F Q267 H358 S359 K363 K366 A431 N434 N435 E438 E441 D442 E445 Q267 H358 S359 K363 K366 A431 N434 N435 E438 E441 D442 E445
BS02 rna F K196 Y210 K211 Y259 E260 M287 H340 K354 H358 R361 R362 N434 E438 K196 Y210 K211 Y259 E260 M287 H340 K354 H358 R361 R362 N434 E438
Gene Ontology
Biological Process
GO:0007165 signal transduction

View graph for
Biological Process
External links
PDB RCSB:8k9g, PDBe:8k9g, PDBj:8k9g
PDBsum8k9g
PubMed37783228
UniProtA0A1I7NFG5

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