Structure of PDB 8k87 Chain F

Receptor sequence

>8k87F (length=468) Species: 35554 (Geobacter sulfurreducens)

SQLAAHSTIPEPLLLFKDNRTDTHPLRGLSQYGPYSACFNLPGQVRLAYL
APTEHMRKLDAIVRELQNPATPKEATNYYVEYGGFEKVFKVPLVMPQEHL
RCLALDECHGVAANGNGLALADKIVQSMSGLFRQKHAFDVLLVYLPASWK
KCFEYDGFDLHDRIKAKVAPLNLPIQIINDTALTRQCRANVMWGVSVALY
AKAGGIPWKLADWDKDEAYIGLSYAIKKNAEGQEYTTCCSQVFDPDGTGF
EFVAYDTREFITDRKGNPYLSYQEMQSVLSKSLHLYQSSHNGRMPRKIFI
HKTTHFTEDEIQGAFDSFSSSTEIELVQIIQSTNWYGLKVDGKKGDKPVA
PASYPVDRGLYQPLTESECLLWTQGSVMGVNQQNPGQPVFKEAALTPLPN
PIMLRRFSGNGGWHATCSSILALTKVDWNNNTLYKKLPVTLVYSQVFADV
VKQTPEIVNEIYDYRFFM

3D structure

• PDB: 8k87 Structural Basis of prokaryotic Argonaute System
• Chain: F
• Resolution: 2.9 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	F	E79 A80 N82 Y84 R190 Y229 A230 I231 T308 I335 Q336 S337 S358 Y359 K396 A398	E74 A75 N77 Y79 R185 Y224 A225 I226 T303 I330 Q331 S332 S353 Y354 K391 A393
BS02	rna	F	F158 D164 H166 K170 I182 N184 T186 A187 R190 Y274 Q379 L400 T401 N405 N434 N435 N436 K440 K441 M473	F153 D159 H161 K165 I177 N179 T181 A182 R185 Y269 Q374 L395 T396 N400 N429 N430 N431 K435 K436 M468
BS03	MG	F	L178 P179 F471	L173 P174 F466

Gene Ontology

Molecular Function

• GO:0003674 molecular_function

Biological Process

• GO:0008150 biological_process

External links

• PDB: RCSB:8k87, PDBe:8k87, PDBj:8k87
• PDBsum: 8k87
• PubMed: 38923459
• UniProt: Q74DF5