Structure of PDB 8jjb Chain F

Receptor sequence
>8jjbF (length=349) Species: 9031 (Gallus gallus) [Search protein sequence]
MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFG
RLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVI
YPTDEREVFLAAYNRRREGREGNVWIAKSSAGAKGEGILISSEASELLDF
IDEQGQVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLR
TSSEPYNSANFQDKTCHLTNHCIQKEYSKNYGRYEEGNEMFFEEFNQYLM
DALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVD
EELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLATSIFIKLHH
3D structure
PDB8jjb Structure-based design and synthesis of BML284 derivatives: A novel class of colchicine-site noncovalent tubulin degradation agents.
ChainF
Resolution2.68 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.25: tubulin--tyrosine ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACP F K74 K150 K184 Y185 K198 D200 H239 T241 I330 K74 K128 K162 Y163 K176 D178 H217 T219 I308
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0036211 protein modification process

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Molecular Function
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Biological Process
External links
PDB RCSB:8jjb, PDBe:8jjb, PDBj:8jjb
PDBsum8jjb
PubMed38430854
UniProtA0A8V0Z8P0

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