Structure of PDB 8ifo Chain F

Receptor sequence
>8ifoF (length=77) Species: 9606 (Homo sapiens) [Search protein sequence]
PKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEIT
KRRRKSCQACRFMKCLKVGMLKEGVRL
3D structure
PDB8ifo ERR gamma-DBD undergoes dimerization and conformational rearrangement upon binding to the downstream site of the DR1 element
ChainF
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna F Y138 H139 Y140 K149 K153 K178 V198 R199 Y15 H16 Y17 K26 K30 K55 V75 R76
BS02 dna F E146 A147 R154 R177 K178 Q181 R184 E23 A24 R31 R54 K55 Q58 R61
BS03 ZN F C164 C170 C180 C183 C41 C47 C57 C60
BS04 ZN F C128 C131 C148 C5 C8 C25
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8ifo, PDBe:8ifo, PDBj:8ifo
PDBsum8ifo
PubMed36944284
UniProtP62508|ERR3_HUMAN Estrogen-related receptor gamma (Gene Name=ESRRG)

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