Structure of PDB 8ieg Chain F

Receptor sequence
>8iegF (length=79) Species: 9606 (Homo sapiens) [Search protein sequence]
RDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTY
TEHAKRKTVTAMDVVYALKRQGRTLYGFG
3D structure
PDB8ieg Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A.
ChainF
Resolution3.44 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna F R35 R45 I46 G48 K79 T80 R13 R23 I24 G26 K57 T58
BS02 dna F P32 R36 R45 P10 R14 R23
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity

View graph for
Molecular Function
External links
PDB RCSB:8ieg, PDBe:8ieg, PDBj:8ieg
PDBsum8ieg
PubMed37633270
UniProtP62805|H4_HUMAN Histone H4 (Gene Name=H4C1)

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