Structure of PDB 8ie3 Chain F

Receptor sequence

>8ie3F (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]

VQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKVGKAPKSACGVCPG
RLRGVRAVRPKVLMRLSKTKKHVSRAYGGSMCAKCVRDRIKRAFLIEEQK
IVVKVLKAQ

3D structure

PDB

8ie3 Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.

Chain

Resolution

3.3 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	F	V2 R4 T6 Y7 R9 R10 L11 S12 Y13 T15 S17 K19 R24 T25 P26 N28 R29 Y34 K36 K37 K40 R54 G55 R57 R60 P61 K62 M65 R66 S68 K69 T70 K72 S75 R76 Y78 G80 R93 I97 Q100	V1 R3 T5 Y6 R8 R9 L10 S11 Y12 T14 S16 K18 R23 T24 P25 N27 R28 Y33 K35 K36 K39 R53 G54 R56 R59 P60 K61 M64 R65 S67 K68 T69 K71 S74 R75 Y77 G79 R92 I96 Q99

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0045296	cadherin binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:0045202	synapse
GO:0070062	extracellular exosome
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:8ie3, PDBe:8ie3, PDBj:8ie3
PDBsum	8ie3
PubMed	37491604
UniProt	P49207\|RL34_HUMAN Large ribosomal subunit protein eL34 (Gene Name=RPL34)