Structure of PDB 8i09 Chain F

Receptor sequence
>8i09F (length=245) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence]
CEELEIVWKNIKAEARALADCEPMLASFYHATLLKHENLGSALSYMLANK
LASPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPL
LYLKGFHALQAYRIGHWLWNKGRRALAIFLQNQVSVSFQVDIHPAAKIGR
GIMLDHATGIVVGETAVIEDDVSILQSVTLGGTGKTSGDRHPKIREGVMI
GAGAKILGNIEVGRGAKIGAGSVVLQPVPPHTTAAGVPARIVGKP
3D structure
PDB8i09 Alkyl gallates inhibit serine O -acetyltransferase in bacteria and enhance susceptibility of drug-resistant Gram-negative bacteria to antibiotics.
ChainF
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.30: serine O-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NF0 F G184 T185 G186 L227 G182 T183 G184 L225
BS02 CYS F R192 H193 R190 H191
BS03 NF0 F M201 G203 K219 I220 G221 A237 M199 G201 K217 I218 G219 A235
BS04 CYS F D157 H158 D155 H156
Gene Ontology
Molecular Function
GO:0009001 serine O-acetyltransferase activity
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
Biological Process
GO:0006535 cysteine biosynthetic process from serine
GO:0008652 amino acid biosynthetic process
GO:0019344 cysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:8i09, PDBe:8i09, PDBj:8i09
PDBsum8i09
PubMed37965540
UniProtA0A0D6I3Y9

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