Structure of PDB 8hsr Chain F

Receptor sequence
>8hsrF (length=361) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
RLVKGYLEISQDGYGFLTENLHNLESRVAIVSAGLIKQYALRAGDYVVGQ
ARPPRENERYATLLKVEAVNNLDPEAAKNRPRFDELTPQFPDRQIRLETT
PDELSTRVIDLLAPIGRGQRGLIVAPPKAGKTTLLKKIANAVLKNEPDIK
VIVLLIDERPEEVTDFRESVQGAEVIASTFDEPPQNHIRVAEFVHERAKR
IVEEGGHVMILLDSITRLARANNLVTPPTGRTLSGGLDSAALYFPKRFLG
AARNIRGGGSLTILATALVETGSRMDDVIFEEFKGTGNMELHLSRRLEER
RIFPAIDILKSGTRREELLLGEEVTHKMWLLRKVLADMDPAEAMEMLLAR
LARTKNNKEFL
3D structure
PDB8hsr Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase from Thermus thermophilus.
ChainF
Resolution4.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna F R290 T291 R231 T232
BS02 ADP F P186 K187 A188 G189 K190 T191 T192 F362 P127 K128 A129 G130 K131 T132 T133 F303
BS03 BEF F R276 L327 R217 L268
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008186 ATP-dependent activity, acting on RNA
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006353 DNA-templated transcription termination

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Molecular Function
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Biological Process
External links
PDB RCSB:8hsr, PDBe:8hsr, PDBj:8hsr
PDBsum8hsr
PubMed36753546
UniProtQ5SJE9

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