Structure of PDB 8hbm Chain F

Receptor sequence
>8hbmF (length=72) Species: 9606 (Homo sapiens) [Search protein sequence]
DELCVVCGDRASGYHYNALTCEGCKGFFRSITKNAVYKCKNGGNCVMDMY
MRRKCQECRLRKCKEMGMLAEC
3D structure
PDB8hbm Structural basis of the farnesoid X receptor/retinoid X receptor heterodimer on inverted repeat DNA
ChainF
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna F E145 R176 Q180 R183 E22 R52 Q56 R59
BS02 dna F Y137 H138 Y139 K148 C196 Y14 H15 Y16 K25 C72
BS03 ZN F C127 C147 C4 C24
BS04 ZN F C163 C169 C179 C182 C39 C45 C55 C58
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8hbm, PDBe:8hbm, PDBj:8hbm
PDBsum8hbm
PubMed37287811
UniProtQ96RI1|NR1H4_HUMAN Bile acid receptor (Gene Name=NR1H4)

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