Structure of PDB 8gju Chain F

Receptor sequence
>8gjuF (length=332) Species: 9606 (Homo sapiens) [Search protein sequence]
EQRFVDKLYTGLIQGQRACLAEAITLVESTHSRKKELAQVLLQKVLLYHR
EQEQSNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVDP
SSCTSGGSLLGDKTRMTELSRDMNAYIRPSPTRGTLGGVTRTTNEAILLC
EGAGYDIILIETVGVGQSEFAVADMVDMFVLLLPPAGGDELQGIKRGIIE
MADLVAVTKSDGDLIVPARRIQAEYVSALKLLRKRSQVWKPKVIRISARS
GEGISEMWDKMKDFQDLMLASGELTAKRRKQQKVWMWNLIQESVLEHFRT
HPTVREQIPLLEQKVLIGALSPGLAADFLLKA
3D structure
PDB8gju Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B 12 delivery and repair.
ChainF
Resolution2.79 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP F D270 E271 D189 E190
BS02 GDP F G153 A154 G155 K156 S157 T158 R196 K290 D292 R330 G72 A73 G74 K75 S76 T77 R115 K209 D211 R249
BS03 MG F S157 D193 E242 S76 D112 E161
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:8gju, PDBe:8gju, PDBj:8gju
PDBsum8gju
PubMed37468522
UniProtQ8IVH4|MMAA_HUMAN Methylmalonic aciduria type A protein, mitochondrial (Gene Name=MMAA)

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