Structure of PDB 8gch Chain F

Receptor sequence

>8gchF (length=131) Species: 9913 (Bos taurus)

IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDV
VVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFS
QTVSAVCLPSASDDFAAGTTCVTTGWGLTRY

3D structure

• PDB: 8gch Gamma-chymotrypsin is a complex of alpha-chymotrypsin with its own autolysis products.
• Chain: F
• Resolution: 1.6 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): H57 D102
• Catalytic site (residue number reindexed from 1): H42 D87
• Enzyme Commision number: 3.4.21.1: chymotrypsin.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	F	I16 E20 P24 S26 W27 P28 W29 Q116 A120 C122	I1 E5 P9 S11 W12 P13 W14 Q101 A105 C107

Gene Ontology

Molecular Function

• GO:0004252 serine-type endopeptidase activity

Biological Process

• GO:0006508 proteolysis

External links

• PDB: RCSB:8gch, PDBe:8gch, PDBj:8gch
• PDBsum: 8gch
• PubMed: 2036388
• UniProt: P00766|CTRA_BOVIN Chymotrypsinogen A