Structure of PDB 8ey9 Chain F

Receptor sequence
>8ey9F (length=605) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
MGKYQVMKRASEVDLSTVKYKAETMKAPHLTGLSFKLFVNLLEAPLIGSL
IVDYLKKDNGMTKIFRNTVIPEEPMFRPEFPSQEPEHDVVIVGEDESPID
RLETALKCLPQYDPSRSLHADPVSSFRYWKIRDYAYAYRSKLTTPLQVAK
RIISIIEEFGYDKPPTPFLIRFDANEVIKQAEASTRRFEQGNPISVLDGI
FVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKAN
MHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGT
DGGGAVRIPSALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDA
FLVYAAILGSSSADRYNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFN
DVSSSDISDKCEDILKLLSNNHGCKVVEIVVPELEEMRAAHVISIGSPTL
SSLTPYCEAGKNSKLSYDTRTSFAIFRSFSASDYIAAQCLRRRLMEYHLN
IFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMRFVLAANLLGF
PAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEELAPVTKKPAIF
YDILN
3D structure
PDB8ey9 Structural interactions explain the versatility of FAAH in the hydrolysis of plant and microbial acyl amide signals
ChainF
Resolution3.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.99: fatty acid amide hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 X4X F G255 T300 G302 G303 G304 A305 V442 S472 I475 M539 G255 T300 G302 G303 G304 A305 V442 S472 I475 M539
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0017064 fatty acid amide hydrolase activity
GO:0047412 N-(long-chain-acyl)ethanolamine deacylase activity
Biological Process
GO:0016042 lipid catabolic process
GO:0042742 defense response to bacterium
GO:0070291 N-acylethanolamine metabolic process
Cellular Component
GO:0000325 plant-type vacuole
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0009536 plastid

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ey9, PDBe:8ey9, PDBj:8ey9
PDBsum8ey9
PubMed
UniProtQ7XJJ7|FAAH_ARATH Fatty acid amide hydrolase (Gene Name=FAAH)

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