Structure of PDB 8eag Chain F

Receptor sequence
>8eagF (length=491) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence]
RVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFE
WPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEV
PSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFD
IYMKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEAL
ALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYT
TGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDED
RVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDN
INLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTL
RKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLE
ALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDM
3D structure
PDB8eag Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation.
ChainF
Resolution3.01 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna F V377 K381 A431 V264 K268 A318
BS02 08T F R473 P559 R560 E563 R360 P446 R447 E450
BS03 ZN F H144 C149 C171 C174 H40 C45 C67 C70
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0032508 DNA duplex unwinding

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Molecular Function
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Biological Process
External links
PDB RCSB:8eag, PDBe:8eag, PDBj:8eag
PDBsum8eag
PubMed36499022
UniProtQ9UXG1|MCM_SACS2 Minichromosome maintenance protein MCM (Gene Name=MCM)

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