Structure of PDB 8b7a Chain F

Receptor sequence
>8b7aF (length=334) Species: 9031 (Gallus gallus) [Search protein sequence]
MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFG
RLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVI
YPDEREVFLAAYNRRREGREGNVWIAKSGILISSEASELLDFIDEVHVIQ
KYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSADK
TCHLTNHCIQKEYSKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQ
IKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAP
ACAQKLYAELCQGIVDVAISSVFPLASIFIKLHH
3D structure
PDB8b7a Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics.
ChainF
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.25: tubulin--tyrosine ligase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ACP F K74 K150 Q183 Y185 L186 K198 T241 N242 D318 E331 N333 K74 K127 Q150 Y152 L153 K165 T205 N206 D282 E295 N297
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0036211 protein modification process

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:8b7a, PDBe:8b7a, PDBj:8b7a
PDBsum8b7a
PubMed36468686
UniProtA0A8V0Z8P0

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