Structure of PDB 8b4m Chain F

Receptor sequence
>8b4mF (length=311) Species: 1901 (Streptomyces clavuligerus) [Search protein sequence]
MTISVPQLDCPLSRPVHPEGERADAYAVEWLRGVGLMADEADAAPVLAVG
LGRLAACYVDENASWDTLAFMTILLAWYAEYDDRAIDSTGLTDAEVAELH
RALGEILRDRPAPDPSDPVQRGLADVWRTLNGLASDWDRAAFVDTTLRYF
EANRYERVNIRRGIPPTPSAHIGMRRHGGHVYGMYILGAAVNGYRPERRV
LDHAAVRELETLAANYTSWANDLHSFAREHRMGQVNNLVWSVHHHEGLTF
QQAADRVADLCDKELAAYLELRQTLPELGIPLTGATGRHVRFLEDMMWSM
VDWSARSARYD
3D structure
PDB8b4m crystal structure of s hydropyrene synthase in its closed conformation
ChainF
Resolution3.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.3.201: hydropyrene synthase.
4.2.3.202: hydropyrenol synthase.
4.2.3.203: isoelisabethatriene synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG F N225 S229 E233 N221 S225 E229
BS02 212 F D82 N225 S229 E233 D82 N221 S225 E229
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8b4m, PDBe:8b4m, PDBj:8b4m
PDBsum8b4m
PubMed
UniProtD5SK09|HPS_STRCL Hydropyrene synthase (Gene Name=SCLAV_p0765)

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