Structure of PDB 8asi Chain F

Receptor sequence

>8asiF (length=432) Species: 272943 (Cereibacter sphaeroides 2.4.1)

MSGIPHDHYEPRTGIEKWLHSRLPIVALAYDTIMIPTPRNLNWMWIWGVV
LAFCLVLQIVTGIVLAMHYTPHVDLAFASVEHIMRNVNGGFMLRYLHANG
ASLFFIAVYLHIFRGLYYGSYKAPREVTWIVGMLIYLAMMATAFMGYVLP
WGQMSFWGATVITGLFGAIPGIGHSIQTWLLGGPAVDNATLNRFFSLHYL
LPFVIAALVAIHIWAFHSTGNNNPTGVEVRRTSKAEAQKDTVPFWPYFII
KDVFALAVVLLVFFAIVGFMPNYLGHPDNYIEANPLSTPAHIVPEWYFLP
FYAILRAFTADVWVVQIANFISFGIIDAKFFGVLAMFGAILVMALVPWLD
TSPVRSGRYRPMFKIYFWLLAADFVILTWVGAQQTTFPYDWISLIASAYW
FAYFLVILPILGAIEKPVAPPATIEEDFNAHY

3D structure

• PDB: 8asi Cryo-EM structure of the four-subunit Rhodobacter sphaeroides cytochrome bc 1 complex in styrene maleic acid nanodiscs.
• Chain: F
• Resolution: 2.9 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	F	W45 G48 L51 A52 H111 R114 R125 W129 G132 M133 I135 H212 F216 N222	W45 G48 L51 A52 H111 R114 R125 W129 G132 M133 I135 H212 F216 N222
BS02	HEM	F	Q58 G62 I63 Y69 R94 H97 T142 G146 Y147 L149 P150 H198 Y199 P202	Q58 G62 I63 Y69 R94 H97 T142 G146 Y147 L149 P150 H198 Y199 P202
BS03	U10	F	M140 A141 F144 G158 V161 I162 W179 L180 L197 I292 P294 F298 Y302	M140 A141 F144 G158 V161 I162 W179 L180 L197 I292 P294 F298 Y302

Gene Ontology

Molecular Function

• GO:0008121 ubiquinol-cytochrome-c reductase activity
• GO:0009055 electron transfer activity
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0022904 respiratory electron transport chain
• GO:1902600 proton transmembrane transport

Cellular Component

• GO:0005886 plasma membrane
• GO:0016020 membrane
• GO:0045275 respiratory chain complex III

External links

• PDB: RCSB:8asi, PDBe:8asi, PDBj:8asi
• PDBsum: 8asi
• PubMed: 36913593
• UniProt: Q3IY10